Not medical advice
Everything on protocols.charlessieg.com describes what I, Charles Sieg, do and summarizes published research for general education. None of it is medical advice, diagnosis, or treatment. I'm not a physician, and reading this site doesn't create a doctor-patient relationship with me or with anyone cited here.
Don't use anything here to diagnose or treat a health problem, and don't start, stop, or change a medication, supplement, diet, or exercise program because of it. Talk to a qualified clinician first, one who knows your history.
Talk to a clinician first, especially if
- you have a heart condition, high or low blood pressure, an arrhythmia, or a history of fainting;
- you have diabetes, take insulin or another glucose-lowering drug (including an SGLT2 inhibitor), or have kidney or liver disease;
- you have a seizure disorder, an eating disorder, or a history of either;
- you're pregnant, trying to become pregnant, or nursing;
- you take any prescription medication, because supplements and diet changes can interact with it;
- you're under 18 or over 65.
Heat and cold carry real risks. Sauna use and hot yoga can be dangerous with heart disease, alcohol, or dehydration, and cold-water immersion can cause cold shock, dangerous heart rhythms, drowning, and hypothermia. Never use a cold plunge or open water alone.
Fasting carries real risks too, especially with diabetes, a glucose-lowering drug, an eating disorder, pregnancy, or low body weight, and short sleep has costs of its own. The fasting and sleep pages describe what I do, not what anyone else should do.
Supplements
Dietary supplements in the United States aren't reviewed by the Food and Drug Administration for safety or effectiveness before they're sold. These statements haven't been evaluated by the Food and Drug Administration, and no product mentioned here is intended to diagnose, treat, cure, or prevent any disease. Labels can be wrong, and products can be contaminated.
Medications
Nuvigil (armodafinil) is a prescription drug and a federally controlled substance, and retatrutide is an investigational drug that the FDA hasn't approved, as of the date on its page. The medication pages describe what the labels and trials report. They aren't a recommendation to take either drug, they give no dose for anyone to take, and they don't say where to get them. Decisions about prescription and investigational drugs belong with a clinician who knows your history.
Research changes
The pages summarize studies as I understand them on the date each page was last reviewed. Studies can be small, short, flawed, or overturned, and a summary can be wrong. Results in a study group don't predict what will happen to you. Check the sources yourself, and rely on your clinician, not on this site.
No endorsements, no money
The researchers, podcasts, companies, and products named here, including Rhonda Patrick, PhD, haven't reviewed or endorsed this site, and I'm not affiliated with any of them. Product and drug names are trademarks of their owners and appear only to describe what I use. This site has no ads, no sponsors, and no affiliate links: where a page links to a product, it's a plain link to where I buy it, and I earn nothing from it.
Links
Links to other sites are for reference. I don't control them and I'm not responsible for their content.
Emergencies
If you think you're having a medical emergency, call 911 or your local emergency number now.